Common subclinical hypothyroidism during Whipple’s disease

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Common subclinical hypothyroidism during Whipple’s disease

BACKGROUND Classic Whipple's disease is caused by T. whipplei and likely involves genetic predispositions, such as the HLA alleles DRB1*13 and DQB1*06, that are more frequently observed in patients. T. whipplei carriage occurs in 2-4% of the general population in France. Subclinical hypothyroidism, characterized by high levels of TSH and normal free tetra-iodothyronine (fT4) dosage, has been ra...

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Subclinical Hypothyroidism and Cardiovascular Disease

Subclinical hypothyroidism (SCH) is a common disorder that is characterized by elevated thyroid-stimulating hormone levels in conjunction with free thyroxine concentrations within the normal reference range. Thyroid hormones are known to affect the heart and vasculature and, as a result, the impact of SCH on the cardiovascular (CV) system has recently become an important topic of research. Stro...

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Whipples disease: a review

Whipple’s disease was described in 1907 and given the name “intestinal lipodystrophy” until it was found that the agent responsible is a bacterium named Tropheryma whipplei. It’s a rare disease which occurs predominantly in males aged 30-60. The small intestinal mucosa is always affected with lesions that are specific to this disease. Replacement of most of cellular elements in the lamina propr...

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Subclinical hypothyroidism.

Subclinical hypothyroidism was detected in 5.7% of 853 patients referred for ambulatory examination to a department in Prague. In patients referred with a mild degree of subclinical hypothyroidism with an evaluated level of thyrotropic hormone in serum (TSH) no significant deviations of serum thyroxine and triiodothyronine (T4 and T3) were found nor different values of the Achilles tendon refle...

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Subclinical hypothyroidism in children.

NEED AND PURPOSE OF REVIEW Subclinical hypothyroidism is a biochemical diagnosis characterized by raised thyroid stimulating hormone and normal free T4, without clinical features of hypothyroidism. This review analyzes the current evidence to arrive at a consensus and algorithm to manage this condition. METHODS We searched Pubmed, Cochrane and Embase for articles published between 1990 to 201...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2014

ISSN: 1471-2334

DOI: 10.1186/1471-2334-14-370